Researcher and retired professor Ramachandra Hosmane’s work over the past 3 decades has been supported by over 40 grants totaling in excess of $10 million from state and federal agencies, private companies, and organizations. Ramachandra Hosmane is currently researching drugs designed to inhibit breast, prostate, and lung cancers, as well as HIV, hepatitis B, and hepatitis C viruses. Dr. Hosmane’s other major research projects include a study on the synthesis of artificial blood, which is sponsored by a grant from the American Heart Association; and a study on the development of antiviral compounds that can be used to treat a range of human viruses, such as influenza A and B, measles, herpes simplex, Japanese encephalitis, and the West Nile virus. A main focus of Ramachandra Hosmane’s research is ring-expanded (“fat”) nucleoside structures.
The results of Dr. Hosmane’s work have appeared in scientific journals worldwide, including Antiviral Research, the Journal of Biological Chemistry, and Organic Letters. His latest research was published in 2011 in Bioorganic & Medicinal Chemistry Letters and concerned transition state analogue inhibitors of the enzyme guanase, and in ACS Medicinal Chemistry Letters and concerned synthesis and biological evaluation of novel, broad-spectrum anticancer agents. Other research by Dr. Hosmane on blood substitutes was published in Bioconjugate Chemistry in 2010. Organizations such as the American Chemical Society and the European Congress of Infectious Diseases and Clinical Microbiology frequently invite Ramachandra Hosmane to lecture on his work. In 2002, Dr. Hosmane was named the Maryland Chemist of the Year by the American Chemical Society.
A member of American Chemical Society and the International Society for Antiviral Research, Ramachandra Hosmane serves as a peer reviewer for numerous chemical journals such as Journal of Organic Chemistry, Tetrahedron, Synthesis, Angewandte Chemie, Journal of Medicinal Chemistry, and Hemoglobin. He has served as the Guest Editor of Bentham Science Publishers’ Current Topics in Medicinal Chemistry and Managing Editor for Frontiers in Bioscience. Dr. Hosmane is currently serving as the Guest Editor for a special issue on Nucleoside Analogues in the journal Molecules published by Molecular Diversity Preservations International (MDPI), Switzerland. Dr. Hosmane also reviews grant proposals for the American Heart Association, the National Institutes of Health, the Food and Drug Administration, American Chemical Society Petroleum Research Funds, and the Guggenheim Foundation.